Children’s Health

Aug 5 2020 Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps (NETs) for severe cases of COVID-19. NETs are a fundamental arm of
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Reviewed by Emily Henderson, B.Sc.Aug 4 2020 Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of–and a treatment for a previously unknown severe auto inflammatory syndrome affecting an 18-year-old girl since infancy. The technology, tailored to the patient’s own genetic code at a single cell
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An early blood test could detect which babies deprived of oxygen at birth are at risk of serious neurodisabilities like cerebral palsy and epilepsy. The prototype test looks for certain genes being switched on and off that are linked to long-term neurological issues. Further investigations of these genes may provide new targets for treating the
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A potentially safer, more effective chemotherapy treatment for patients with blood-related cancers, such as leukemia, who need a particular bone marrow transplant procedure is under study at the University of Arizona Health Sciences. The procedure is known as a haploidentical (half-matched) bone marrow transplantation, or “haplo-BMT,” providng an alternative source of stem cells for patients
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A mother’s own breast milk has infection-fighting factors and nutrients to help fuel growth and development in babies and may be easier to digest than formula. Providing this nourishment is particularly important for infants born prematurely, both while they are receiving care in a hospital’s neonatal intensive care unit (NICU) and after they are able
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Reviewed by Emily Henderson, B.Sc.Jul 31 2020 Researchers led by a team at Rosalind Franklin University of Medicine and Science have devised a new therapeutic approach to treating a rare but deadly neurodegenerative genetic disease in children. The study, published this week in Nature Medicine, addresses the urgent need to discover treatments for Batten disease,
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A new study by researchers at University of Illinois at Urbana-Champaign and Brookhaven National Laboratory and published on the preprint server medRxiv* in July 2020 discusses the effect of a factor called persistent contact heterogeneity on the final epidemic size of COVID-19. The researchers say that using estimates based on this measure reduces the herd
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Doctoral candidate of the Education Programme of Castellón’s Jaume I University (UJI), Juan Vives Vilarroig, has highlighted in his thesis the importance of working on basic aspects such as balance and postural control to improve sensory integration in children with autism spectrum disorders, using horses as the main elements of this intervention. Resesarch project “Efectos
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Reviewed by Emily Henderson, B.Sc.Jul 30 2020 The Faculty of Medicine has awarded 58 clinical research chairs to top clinician-scientists in a five-year, $40 million investment to drive clinical research excellence and enhance health and patient care. The University of Ottawa Faculty of Medicine Clinical Research Chairs span four categories — Distinguished, Tier 1, Tier
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Reviewed by Emily Henderson, B.Sc.Jul 29 2020 Boston Medical Center’s StreetCred program has been named to the second cohort of the Aspen Family Prosperity Innovation Community, an Aspen Institute initiative for breakthrough innovations and collaborations that position families to reach educational success, economic prosperity, and health and well-being. The launch of this community, Ascend, could
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The Damon Runyon Cancer Research Foundation has named two outstanding young scientists as recipients of the Damon Runyon-Sohn Pediatric Cancer Fellowship Award, committing nearly $500,000 to help address a critical shortage of funding for pediatric cancer research. The Fellowship Award provides funding to basic scientists and clinicians who conduct research with the potential to significantly
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A new technique that can spot a potential preterm birth in asymptomatic high-risk women, with up to 73% accuracy months before delivery, has been developed by scientists at the University of Warwick. Utilising cutting-edge volatile organic compound analysis technology, designed to characterise airborne chemicals, the scientists ‘trained’ the device using machine-learning techniques to identify the
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Reviewed by Emily Henderson, B.Sc.Jul 28 2020 Depression in mothers during and after pregnancy increased the odds of depression in offspring during adolescence and adulthood by 70%, according to a new study by researchers at The University of Texas Health Science Center at Houston (UTHealth). The systematic review was recently published in JAMA Network Open.
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Reviewed by Emily Henderson, B.Sc.Jul 27 2020 Appendicitis is the most common cause for emergency abdominal surgery in childhood, affecting 80,000 children in the United States each year, but nonoperative treatment options are viable. A study performed by the Midwest Pediatric Surgery Consortium, led by Peter Minneci, MD, and Katherine Deans, MD, co-founders and directors
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