Children’s Health

Reviewed by Emily Henderson, B.Sc.Oct 30 2020 Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School. The projects, which target a diverse range of conditions–type 1 diabetes, asthma, frontotemporal dementia, deadly cancer-associated blood clots, and a rare congenital
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Researchers in the UK have conducted a study showing that families and school staff support the use of coronavirus disease 2019 (COVID-19) mitigation measures in secondary schools as young people return to face-to-face education. The team’s study of attitudes towards mitigation measures among young people, parents, and school staff found that, although some participants expressed
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Reviewed by Emily Henderson, B.Sc.Oct 29 2020 University Hospitals (UH) and Case Western Reserve University (CWRU) announced today that UH Cleveland Medical Center has been selected as a clinical trial site for the Phase 3 global study of an investigational vaccine against SARS-CoV-2, sponsored by AstraZeneca. The trial is funded by the National Institute of
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Reviewed by Emily Henderson, B.Sc.Oct 29 2020 Since 2017, University of Alabama at Birmingham researchers Casey Morrow, Ph.D., and Hyunmin Koo, Ph.D., have used powerful genomic tools and supercomputers that analyze massive amounts of genetic data to identify individual strains within single species of the gut microbiome. This microbiome “fingerprint” method has helped show the
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Reviewed by Emily Henderson, B.Sc.Oct 28 2020 Women with epilepsy who take the antiseizure drug valproic acid while pregnant are at more than double the risk of having children with autism spectrum disorder and nearly double the risk of having children with attention deficit hyperactivity disorder (ADHD), according to a study in the October 28,
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Reviewed by Emily Henderson, B.Sc.Oct 28 2020 Handgun sales in California have risen to unprecedented levels during the COVID-19 pandemic, and experts say first-time buyers are driving the trend. The FBI conducted 462,000 background checks related to handgun purchases in California from March through September, an increase of 209,000, or 83%, from the same period
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Reviewed by Emily Henderson, B.Sc.Oct 28 2020 While an infant’s genes distinguish her from other newborns, a new peer-reviewed study reports that specific genes of a particular infant gut bacterium determine its symbiotic function in the infant’s gut. The study provides important guidance for clinicians when selecting a probiotic for use in infants to maximize
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Reviewed by Emily Henderson, B.Sc.Oct 27 2020 Arizona-based Critical Path Institute (C-Path) is pleased to announce it has been awarded a multi-year grant by the U.S. Food and Drug Administration (FDA) to advance standards and methodologies designed to generate real-world evidence (RWE) from real-world data (RWD) through a neonatal pilot project through the International Neonatal
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Reviewed by Emily Henderson, B.Sc.Oct 27 2020 Researchers have revealed the key factors that can improve outcomes in children with ADHD, a disorder that costs Australia US$13 billion a year in social and economic losses. Research, led by the Murdoch Children’s Research Institute (MCRI) and published in Pediatrics, highlighted the importance of identifying academic, behavioral
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Reviewed by Emily Henderson, B.Sc.Oct 27 2020 Research from Saint Louis University finds that high fat or “ketogenic” diets could completely prevent, or even reverse heart failure caused by a metabolic process. The research team, led by Kyle S. McCommis, Ph.D., assistant professor in Biochemistry and Molecular Biology at SLU, looked at a metabolic process
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By using a diverse set of transcriptomic SARS-CoV-2 signatures, US researchers put to use their previously developed drug repositioning pipeline to pinpoint potential drug candidates for the treatment of coronavirus disease (COVID-19). The study is currently available on the bioRxiv* preprint server. While many efforts are currently underway to identify potential therapies targeting various aspects
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Researchers at Simon Fraser University in Canada have warned that within the school setting, even small differences in individuals’ contribution, their environment, and their activities to the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) result in highly variable sizes of transmission clusters. SARS-CoV-2 is the virus responsible for the current coronavirus disease 2019
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Reviewed by Emily Henderson, B.Sc.Oct 23 2020 The results of a new clinical trial, published today in the New England Journal of Medicine, show that dexamethasone- a glucocorticoid used to treat many conditions, including rheumatic problems and severe COVID-19- can boost survival of premature babies when given to pregnant women at risk of preterm birth
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Reviewed by Emily Henderson, B.Sc.Oct 22 2020 Jeffery Dusek, PhD, Director of Research at University Hospitals (UH) Connor Integrative Health Network and Associate Professor in the Department of Family Medicine and Community Health at Case Western Reserve University, and colleagues were recently awarded a 3-year, $2+ million grant from the National Center of Complementary and
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Reviewed by Emily Henderson, B.Sc.Oct 23 2020 With nearly half of the world’s population at risk for life-threatening malaria infections, University of Maryland School of Medicine (UMSOM) researchers and their colleagues identified an important public health measure to control the disease. Use of preventive antimalarial treatments reduces by half the number of malaria infections among
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Reviewed by Emily Henderson, B.Sc.Oct 22 2020 New questions are at the forefront as a study published in the Journal of Clinical Microbiology from nine children’s hospitals finds that most asymptomatic children who tested positive for COVID-19 had relatively low levels of the virus compared to symptomatic children. The authors caution that the reason for
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Reviewed by Emily Henderson, B.Sc.Oct 22 2020 The Alzheimer’s Biomarkers Consortium – Down Syndrome (ABC-DS), a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health (NIH), to expand research on the biomarkers of Alzheimer’s disease in adults
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