Children’s Health

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease. The discovery of the mutation, which weakens the activity of a protein linked to how the immune system fights viruses in the gut, may help
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Researchers in the United States have provided important insights into the antigen-specific cellular response and evolving humoral (antibody) response to messenger RNA- (mRNA) based vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19). Using single-cell profiling technologies and machine learning analyses, the team identified and characterized
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People with type 2 diabetes diagnosed during youth have a high risk of developing complications at early ages and have a greater chance of multiple complications within 15 years after diagnosis. The findings are the culmination of a first-of-its-kind trial funded largely by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part
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With the onset of coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), scientists began an intensive effort to develop vaccines against the virus. These efforts were largely fueled by predictions that public health interventions would inevitably cripple the global economy if continued indefinitely. In the United States,
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that caused the coronavirus disease 2019 (COVID-19) pandemic, has affected the USA both physically and economically. Typically mild or asymptomatic in children, it has caused sequelae such as the multisystem inflammatory syndrome in children (MIS-C), which may set in after the virus has been cleared
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Adolescents who set goals for their future and those with strong parental support are less likely to use e-cigarettes and other tobacco products, according to a study by UPMC Children’s Hospital of Pittsburgh and University of Pittsburgh School of Medicine physician-scientists. The research, published today in the journal Pediatrics, suggests that strategies to prevent youth
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Most children with a mental health disorder are not receiving services to address their needs–according to a new study from researchers at Simon Fraser University’s Children’s Health Policy Centre. Their research was published this week in the journal Evidence-Based Mental Health. Researchers found that of the one in eight children (12.7 per cent) who experience
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Chemotherapy has helped make acute lymphoblastic leukemia (ALL) one of the most survivable childhood cancers. Now, researchers working in the U.S., Germany and China have shown how chemotherapy drugs called thiopurines can lead to mutations that set patients up for relapse. The work appears today in the journal Nature Cancer. The research provides the first
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New research shows that 3-year-old toddlers had lower blood pressure when they were breastfed as babies in comparison to ones that weren’t. Woman Breastfeeding. Image Credit: Kingspirit Image Room/Shutterstock.com Exploring cardiovascular disease risk factors in early childhood The development and onset of risk factors for medical conditions such as cardiovascular disease has remained elusive, but
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As children made fewer visits to health facilities and engaged in social distancing and other COVID-19 mitigation measures, a smaller number of them also received prescription drugs, a new study suggests. Overall, medications prescribed for children dropped by more than a quarter during the first eight months of the pandemic compared to the previous year,
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Parach Sirivichayakul, Mahidol University, Bangkok, Thailand, presented the poster “Preventing Approximal Caries in Primary Teeth With Topical Fluorides” at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting
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Evaluating the efficacy of novel therapies requires the ability to monitor wound progression accurately and reproducibly over time. Researchers have proposed a new scoring system for wound healing in mice based on parameters in each phase of healing, as described in an article in the peer-reviewed journal Stem Cells and Development. The parameters include re-epithelization,
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Up to 2,000 children and young adults will be enrolled in a study from Children’s National Hospital in collaboration with the National Institute of Allergy and Infectious Diseases (NIAID) that will examine the long-term effects of COVID-19 and multisystem inflammatory syndrome in children (MIS-C) after these patients have recovered from a COVID-19 infection. This $40
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